Ultrasound-assisted one-pot green synthesis of new N- substituted-5-arylidene-thiazolidine-2,4-dione-isoxazoline derivatives using NaCl/Oxone/Na3PO4 in aqueous media
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چکیده
منابع مشابه
Microwave-assisted synthesis and evaluation of N-substituted thiazolidine-2, 4-dione derivatives as antimicrobial agents
A series of N-substituted thiazolidine-2,4-dione derivatives bearing potentially bioactive substituents were synthesized by microwave irradiation method. Structural elucidation was accomplished by 1H NMR, 13C NMR, IR, Mass and elemental analyses. The synthesized compounds were evaluated for antimicrobial activities. Among the compounds studied, compounds 4i and 4d showed potent antimicrobial ac...
متن کاملSynthesis and Antimicrobial Activities of 5-Arylidene-thiazolidine-2,4-dione Derivatives
Antibiotic resistance is considered one of the world's major public health concerns. The main cause of bacterial resistance is the improper and repeated use of antibiotics. To alleviate this problem, new chemical substances against microorganisms are being synthesized and tested. Thiazolidines are compounds having many pharmacological activities including antimicrobial activities. For this purp...
متن کاملOne-pot synthesis of functionalized thiazolidine-4-ones from thiosemicarbazone derivatives and activated acetylenes in water as a green solvent
Some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. The reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. All the synthesized compounds were characterized by their physical and spectral data.
متن کاملOne-pot synthesis of functionalized thiazolidine-4-ones from thiosemicarbazone derivatives and activated acetylenes in water as a green solvent
Some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. The reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. All the synthesized compounds were characterized by their physical and spectral data.
متن کاملOne-pot, organocatalytic synthesis of spirooxindoles using citric acid in aqueous media
Spirooxindoles are important synthetic targets possessing extended biological activity and drug discovery applications.The development of multicomponent reactions designed to produce elaborate biologically active compounds has become an important area of research in organic, combinatorial, and medicinal chemistry. in this Manuscript, a facile and efficient multicomponent synthesis of functional...
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ژورنال
عنوان ژورنال: Ultrasonics Sonochemistry
سال: 2020
ISSN: 1350-4177
DOI: 10.1016/j.ultsonch.2020.105222